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Anionic Lipids Allosterically Modulate Multiple Nicotinic Acetylcholine Receptor Conformational Equilibria

Anionic lipids influence the ability of the nicotinic acetylcholine receptor to gate open in response to neurotransmitter binding, but the underlying mechanisms are poorly understood. We show here that anionic lipids with relatively small headgroups, and thus the greatest ability to influence lipid...

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Detalhes bibliográficos
Main Authors: daCosta, Corrie J. B., Medaglia, Sarah A., Lavigne, Nadine, Wang, Shuzhi, Carswell, Casey L., Baenziger, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797154/
https://ncbi.nlm.nih.gov/pubmed/19815550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.048280
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