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Nicotinic acetylcholine receptor α1 promotes calpain-1 activation and macrophage inflammation in hypercholesterolemic nephropathy

The nicotinic acetylcholine receptor α1 (nAChRα1) was investigated as a potential proinflammatory molecule in the kidney, given a recent report that it is an alternative urokinase plasminogen activator (uPA) receptor, in addition to the classical receptor uPAR. Two animal models and in vitro monocyt...

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Main Authors: Zhang, Guoqiang, Thomas, Alison L, Marshall, Amanda L, Kernan, Kelly A, Su, Yanyuan, Zheng, Yi, Takano, Jiro, Saido, Takaomi C, Eddy, Allison A
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188436/
https://ncbi.nlm.nih.gov/pubmed/20661225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.135
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