A Truncated Diphtheria Toxin Based Recombinant Porcine CTLA-4 Fusion Toxin

Targeted cell therapies are possible through the generation of recombinant fusion proteins that combine a toxin, such as diphtheria toxin (DT), with an antibody or other molecule that confers specificity. Upon binding of the fusion protein to the cell of interest, the diphtheria toxin is internalize...

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Autori principali: Peraino, Jaclyn Stromp, Schenk, Marian, Zhang, Huiping, Li, Guoying, Hermanrud, Christina E., Neville, David M., Sachs, David H., Huang, Christene A., Duran-Struuck, Raimon, Wang, Zhirui
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688055/
https://ncbi.nlm.nih.gov/pubmed/23470981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2013.02.015
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