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Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25(+) cells

Regulatory T cells (Treg) constitute a major inhibitory cell population which suppresses immune responses. Thus, Treg have proven to be key players in the induction of transplantation tolerance, protection from autoimmune disease and prevention of the development of effective anti-tumor immune react...

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Detalhes bibliográficos
Main Authors: Peraino, Jaclyn Stromp, Zhang, Huiping, Rajasekera, Priyani V., Wei, Min, Madsen, Joren C., Sachs, David H., Huang, Christene A., Wang, Zhirui
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120078/
https://ncbi.nlm.nih.gov/pubmed/24462799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.01.008
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