Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25(+) cells

Regulatory T cells (Treg) constitute a major inhibitory cell population which suppresses immune responses. Thus, Treg have proven to be key players in the induction of transplantation tolerance, protection from autoimmune disease and prevention of the development of effective anti-tumor immune react...

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Main Authors: Peraino, Jaclyn Stromp, Zhang, Huiping, Rajasekera, Priyani V., Wei, Min, Madsen, Joren C., Sachs, David H., Huang, Christene A., Wang, Zhirui
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120078/
https://ncbi.nlm.nih.gov/pubmed/24462799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.01.008
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