Diphtheria‐toxin based anti‐human CCR4 immunotoxin for targeting human CCR4+ cells in vivo

CC chemokine receptor 4 (CCR4) has attracted much attention as a promising therapeutic drug target for CCR4+ tumor cells and Tregs. CCR4 is expressed on some tumor cells such as T‐cell acute lymphoblastic leukemia (ALL), adult T‐cell leukemia/lymphoma (ATLL), adult peripheral T cell lymphoma (PTCL)...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Wang, Zhaohui, Wei, Min, Zhang, Huiping, Chen, Hongyuan, Germana, Sharon, Huang, Christene A., Madsen, Joren C., Sachs, David H., Wang, Zhirui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528803/
https://ncbi.nlm.nih.gov/pubmed/25958791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.04.004
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