Porcine Treg depletion with a novel diphtheria toxin-based anti-human CCR4 immunotoxin

Regulatory T cells (Tregs) are known to play an important role in immunoregulation and have been shown to facilitate induction of transplantation tolerance. Chemokine (C-C motif) receptor 4 (CCR4) is expressed on the surface of effector Tregs involved in controlling alloimmune and autoimmune respons...

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Gepubliceerd in:Vet Immunol Immunopathol
Hoofdauteurs: Wang, Zhaohui, Navarro-Alvarez, Nalu, Shah, Jigesh A., Zhang, Huiping, Huang, Qi, Zheng, Qian, Madsen, Joren C., Sachs, David H., Huang, Christene A., Wang, Zhirui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134928/
https://ncbi.nlm.nih.gov/pubmed/27863545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2016.10.014
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