Loading...
Tumor suppression in the absence of p53-mediated cell cycle arrest, apoptosis, and senescence
Cell-cycle arrest, apoptosis, and senescence are widely accepted as major mechanisms by which p53 inhibits tumor formation. Nevertheless, it remains unclear whether they are rate-limiting steps in tumor suppression. Here, we have generated mice bearing lysine to arginine mutations at one (p53(K117R)...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3688046/ https://ncbi.nlm.nih.gov/pubmed/22682249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.04.026 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|