Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension

AIMS: Pulmonary arterial hypertension (PAH) occurs more frequently in women than men. Oestrogen and the oestrogen-metabolising enzyme cytochrome P450 1B1 (CYP1B1) play a role in the development of PAH. Anorectic drugs such as dexfenfluramine (Dfen) have been associated with the development of PAH. D...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Dempsie, Yvonne, MacRitchie, Neil A., White, Kevin, Morecroft, Ian, Wright, Audrey F., Nilsen, Margaret, Loughlin, Lynn, Mair, Kirsty M., MacLean, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687748/
https://ncbi.nlm.nih.gov/pubmed/23519266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt064
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares