Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH

Pulmonary arterial hypertension (PAH) is up to threefold more prevalent in women than men. Female mice overexpressing the serotonin transporter (SERT; SERT+ mice) exhibit PAH and exaggerated hypoxia-induced PAH, whereas male SERT+ mice remain unaffected. To further investigate these sex differences,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: White, Kevin, Loughlin, Lynn, Maqbool, Zakia, Nilsen, Margaret, McClure, John, Dempsie, Yvonne, Baker, Andrew H., MacLean, Margaret R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2011
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092337/
https://ncbi.nlm.nih.gov/pubmed/21303932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00249.2010
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