Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH

Pulmonary arterial hypertension (PAH) is up to threefold more prevalent in women than men. Female mice overexpressing the serotonin transporter (SERT; SERT+ mice) exhibit PAH and exaggerated hypoxia-induced PAH, whereas male SERT+ mice remain unaffected. To further investigate these sex differences,...

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Detaylı Bibliyografya
Asıl Yazarlar: White, Kevin, Loughlin, Lynn, Maqbool, Zakia, Nilsen, Margaret, McClure, John, Dempsie, Yvonne, Baker, Andrew H., MacLean, Margaret R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2011
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092337/
https://ncbi.nlm.nih.gov/pubmed/21303932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00249.2010
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