Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH

Pulmonary arterial hypertension (PAH) is up to threefold more prevalent in women than men. Female mice overexpressing the serotonin transporter (SERT; SERT+ mice) exhibit PAH and exaggerated hypoxia-induced PAH, whereas male SERT+ mice remain unaffected. To further investigate these sex differences,...

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Главные авторы: White, Kevin, Loughlin, Lynn, Maqbool, Zakia, Nilsen, Margaret, McClure, John, Dempsie, Yvonne, Baker, Andrew H., MacLean, Margaret R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2011
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092337/
https://ncbi.nlm.nih.gov/pubmed/21303932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00249.2010
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