Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females

BACKGROUND: Idiopathic and familial forms of pulmonary arterial hypertension (PAH) occur more frequently in women than men. However, the reason for this remains unknown. Both the calcium binding protein S100A4/Mts1 (Mts1) and its endogenous receptor (receptor for advanced glycosylation end products;...

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Autors principals: Dempsie, Yvonne, Nilsen, Margaret, White, Kevin, Mair, Kirsty M, Loughlin, Lynn, Ambartsumian, Noona, Rabinovitch, Marlene, MacLean, Margaret R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276452/
https://ncbi.nlm.nih.gov/pubmed/22185646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-159
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