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Regulated recycling of mutant CFTR is partially restored by pharmacological treatment
Efficient trafficking of the cystic fibrosis transmembrane conductance regulator (CFTR) to and from the cell surface is essential for maintaining channel density at the plasma membrane (PM) and ensuring proper physiological activity. The most common mutation, F508del, exhibits reduced surface expres...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3687701/ https://ncbi.nlm.nih.gov/pubmed/23572510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.120196 |
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