Pharmacological Rescue of the Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Detected by Use of a Novel Fluorescence Platform

Numerous human diseases arise because of defects in protein folding, leading to their degradation in the endoplasmic reticulum. Among them is cystic fibrosis (CF), caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR ), an epithelial anion channel. The most commo...

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Detaylı Bibliyografya
Asıl Yazarlar: Holleran, John P, Glover, Matthew L, Peters, Kathryn W, Bertrand, Carol A, Watkins, Simon C, Jarvik, Jonathan W, Frizzell, Raymond A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: ScholarOne 2012
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388127/
https://ncbi.nlm.nih.gov/pubmed/22396015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00001
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