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MAPs: a database of modular antibody parts for predicting tertiary structures and designing affinity matured antibodies

BACKGROUND: The de novo design of a novel protein with a particular function remains a formidable challenge with only isolated and hard-to-repeat successes to date. Due to their many structurally conserved features, antibodies are a family of proteins amenable to predictable rational design. Design...

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Detalhes bibliográficos
Main Authors: Pantazes, Robert J, Maranas, Costas D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687570/
https://ncbi.nlm.nih.gov/pubmed/23718826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-168
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