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Mapping protein interactions by combining antibody affinity maturation and mass spectrometry
Mapping protein interactions by immunoprecipitation is limited by the availability of antibodies recognizing available native epitopes within protein complexes with sufficient affinity. Here we demonstrate a scalable approach for generation of such antibodies using phage display and affinity maturat...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Academic Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171153/ https://ncbi.nlm.nih.gov/pubmed/21704603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.05.005 |
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