Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display

To demonstrate the utility of phage display in generating highly specific antibodies, affinity selections were conducted on 20 related Src Homology 2 (SH2) domains (ABL1, ABL2, BTK, BCAR3, CRK, FYN, GRB2, GRAP2, LYN, LCK, NCK1, PTPN11 C, PIK3R1 C, PLCγ1 C, RASA1 C, SHC1, SH2D1A, SYK N, VAV1 and the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pershad, K., Pavlovic, J.D., Gräslund, S., Nilsson, P., Colwill, K., Karatt-Vellatt, A., Schofield, D.J., Dyson, M.R., Pawson, T., Kay, B.K., McCafferty, J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2010
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841545/
https://ncbi.nlm.nih.gov/pubmed/20164216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq003
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