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Computational de novo Design of Antibodies binding to a Peptide with High Affinity
Antibody drugs play a critical role in infectious diseases, cancer, autoimmune diseases, and inflammation. However, experimental methods for the generation of therapeutic antibodies such as using immunized mice or directed evolution remain time consuming and cannot target a specific antigen epitope....
Gorde:
| Argitaratua izan da: | Biotechnol Bioeng |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5726764/ https://ncbi.nlm.nih.gov/pubmed/28059445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26244 |
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