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Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol

OBJECTIVE: Niacin potently lowers triglycerides, mildly decreases LDL-cholesterol, and largely increases HDL-cholesterol. Despite evidence for an atheroprotective effect of niacin from previous small clinical studies, the large outcome trials, AIM-HIGH and HPS2-THRIVE did not reveal additional benef...

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Detaylı Bibliyografya
Asıl Yazarlar: Kühnast, Susan, Louwe, Mieke C., Heemskerk, Mattijs M., Pieterman, Elsbet J., van Klinken, Jan B., van den Berg, Sjoerd A. A., Smit, Johannes W. A., Havekes, Louis M., Rensen, Patrick C. N., van der Hoorn, José W. A., Princen, Hans M. G., Jukema, J. Wouter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686722/
https://ncbi.nlm.nih.gov/pubmed/23840481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066467
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