Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol

OBJECTIVE: Niacin potently lowers triglycerides, mildly decreases LDL-cholesterol, and largely increases HDL-cholesterol. Despite evidence for an atheroprotective effect of niacin from previous small clinical studies, the large outcome trials, AIM-HIGH and HPS2-THRIVE did not reveal additional benef...

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Detalhes bibliográficos
Main Authors: Kühnast, Susan, Louwe, Mieke C., Heemskerk, Mattijs M., Pieterman, Elsbet J., van Klinken, Jan B., van den Berg, Sjoerd A. A., Smit, Johannes W. A., Havekes, Louis M., Rensen, Patrick C. N., van der Hoorn, José W. A., Princen, Hans M. G., Jukema, J. Wouter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686722/
https://ncbi.nlm.nih.gov/pubmed/23840481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066467
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