Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol

OBJECTIVE: Niacin potently lowers triglycerides, mildly decreases LDL-cholesterol, and largely increases HDL-cholesterol. Despite evidence for an atheroprotective effect of niacin from previous small clinical studies, the large outcome trials, AIM-HIGH and HPS2-THRIVE did not reveal additional benef...

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Bibliografski detalji
Glavni autori: Kühnast, Susan, Louwe, Mieke C., Heemskerk, Mattijs M., Pieterman, Elsbet J., van Klinken, Jan B., van den Berg, Sjoerd A. A., Smit, Johannes W. A., Havekes, Louis M., Rensen, Patrick C. N., van der Hoorn, José W. A., Princen, Hans M. G., Jukema, J. Wouter
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686722/
https://ncbi.nlm.nih.gov/pubmed/23840481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066467
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