Fenofibrate Increases Very Low Density Lipoprotein Triglyceride Production Despite Reducing Plasma Triglyceride Levels in APOE*3-Leiden.CETP Mice

The peroxisome proliferator-activated receptor alpha (PPARα) activator fenofibrate efficiently decreases plasma triglycerides (TG), which is generally attributed to enhanced very low density lipoprotein (VLDL)-TG clearance and decreased VLDL-TG production. However, because data on the effect of feno...

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Detalhes bibliográficos
Main Authors: Bijland, Silvia, Pieterman, Elsbet J., Maas, Annemarie C. E., van der Hoorn, José W. A., van Erk, Marjan J., van Klinken, Jan B., Havekes, Louis M., van Dijk, Ko Willems, Princen, Hans M. G., Rensen, Patrick C. N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919079/
https://ncbi.nlm.nih.gov/pubmed/20501652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123992
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