The dual PPARα/γ agonist tesaglitazar blocks progression of pre-existing atherosclerosis in APOE*3Leiden.CETP transgenic mice

BACKGROUND AND PURPOSE: We have evaluated the effects of a peroxisome proliferator-activated receptor (PPAR)α/γ agonist on the progression of pre-existing atherosclerotic lesions in APOE*3Leiden.cholesteryl ester transfer protein (E3L.CETP) transgenic mice. EXPERIMENTAL APPROACH: E3L.CETP mice were...

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Main Authors: van der Hoorn, JWA, Jukema, JW, Havekes, LM, Lundholm, E, Camejo, G, Rensen, PCN, Princen, HMG
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2009
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Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697696/
https://ncbi.nlm.nih.gov/pubmed/19220285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00109.x
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