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Efficiency of High Molecular Weight Backbone Degradable HPMA Copolymer – Prostaglandin E(1) Conjugate in Promotion of Bone Formation in Ovariectomized Rats

Multiblock, high molecular weight, linear, backbone degradable HPMA copolymer-prostaglandin E(1) (PGE(1)) conjugate has been synthesized by RAFT polymerization mediated by a new bifunctional chain transfer agent (CTA), which contains an enzymatically degradable oligopeptide sequence flanked by two d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pan, Huaizhong, Sima, Monika, Miller, Scott C., Kopečková, Pavla, Yang, Jiyuan, Kopeček, Jindřich
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686554/
https://ncbi.nlm.nih.gov/pubmed/23731780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.05.003
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