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The cell cycle inhibitor p27(Kip1) controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist

The continued turn over of human embryonic stem cells (hESC) while maintaining an undifferentiated state is dependent on the regulation of the cell cycle. Here we asked the question if a single cell cycle gene could regulate the self-renewal or pluripotency properties of hESC. We identified that the...

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Sonraí Bibleagrafaíochta
Main Authors: Menchón, Cristina, Edel, Michael J., Izpisua Belmonte, Juan Carlos
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685623/
https://ncbi.nlm.nih.gov/pubmed/21478681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.9.15421
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