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The cell cycle inhibitor p27(Kip1) controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist

The continued turn over of human embryonic stem cells (hESC) while maintaining an undifferentiated state is dependent on the regulation of the cell cycle. Here we asked the question if a single cell cycle gene could regulate the self-renewal or pluripotency properties of hESC. We identified that the...

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Bibliografski detalji
Glavni autori: Menchón, Cristina, Edel, Michael J., Izpisua Belmonte, Juan Carlos
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685623/
https://ncbi.nlm.nih.gov/pubmed/21478681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.9.15421
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