The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue

BACKGROUND: Recent studies revealed that autophagy is up-regulated in obese individuals, as evidenced by increased expression of autophagy related genes. As argued elsewhere, it is possible that initially insulin resistance functions as an adaptive mechanism to increase autophagy in order to protect...

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Bibliographic Details
Main Authors: Kosacka, Joanna, Koch, Karoline, Gericke, Martin, Nowicki, Marcin, Heiker, John T, Klöting, Ingrid, Stumvoll, Michael, Blüher, Matthias, Klöting, Nora
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685536/
https://ncbi.nlm.nih.gov/pubmed/23668414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-5996-5-23
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