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The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue

BACKGROUND: Recent studies revealed that autophagy is up-regulated in obese individuals, as evidenced by increased expression of autophagy related genes. As argued elsewhere, it is possible that initially insulin resistance functions as an adaptive mechanism to increase autophagy in order to protect...

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Detalhes bibliográficos
Main Authors: Kosacka, Joanna, Koch, Karoline, Gericke, Martin, Nowicki, Marcin, Heiker, John T, Klöting, Ingrid, Stumvoll, Michael, Blüher, Matthias, Klöting, Nora
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685536/
https://ncbi.nlm.nih.gov/pubmed/23668414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-5996-5-23
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