Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of high fat diet-induced obesity by counteracting adipose tissue inflammation in vivo

Vaspin is an adipokine which improves glucose metabolism and insulin sensitivity in obesity. Kallikrein 7 (KLK7) is the first known protease target inhibited by vaspin and a potential target for the treatment of metabolic disorders. Here, we tested the hypothesis that inhibition of KLK7 in adipose t...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Zieger, Konstanze, Weiner, Juliane, Kunath, Anne, Gericke, Martin, Krause, Kerstin, Kern, Matthias, Stumvoll, Michael, Klöting, Nora, Blüher, Matthias, Heiker, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769829/
https://ncbi.nlm.nih.gov/pubmed/28932870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2658-y
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