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Vaspin inhibits kallikrein 7 by serpin mechanism
The molecular target of the adipokine vaspin (visceral adipose tissue-derived serpin; serpinA12) and its mode of action are unknown. Here, we provide the vaspin crystal structure and identify human kallikrein 7 (hK7) as a first protease target of vaspin inhibited by classical serpin mechanism with h...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SP Birkhäuser Verlag Basel
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689916/ https://ncbi.nlm.nih.gov/pubmed/23370777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1258-8 |
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