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Plasma and Cerebrospinal Fluid Pharmacokinetics of Thalidomide and Lenalidomide in Nonhuman Primates
PURPOSE: Thalidomide, originally developed as a sedative, was subsequently identified to have antiangiogenic properties. Lenalidomide is an antiangiogenic and immunomodulatory agent that has been utilized in the treatment of patients with brain tumors. We studied the pharmacokinetics and cerebrospin...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685292/ https://ncbi.nlm.nih.gov/pubmed/22109830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-011-1781-y |
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