Endothelial Cells Overexpressing Interleukin-8 (IL8) Receptors Reduce Inflammatory and Neointimal Responses to Arterial Injury

BACKGROUND: Interleukin-8 (IL8) receptors IL8RA and IL8RB on neutrophil membranes bind to IL8 and direct neutrophil recruitment to sites of inflammation, including acutely injured arteries. This study tested whether administration of IL8RA- and/or IL8RB-transduced rat aortic endothelial cells (ECs)...

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Autori principali: Xing, Dongqi, Li, Peng, Gong, Kaizheng, Yang, Zhengqin, Yu, Hao, Hage, Fadi G., Oparil, Suzanne, Chen, Yiu-Fai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685282/
https://ncbi.nlm.nih.gov/pubmed/22361324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.078436
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