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Targeted delivery of human iPS-ECs overexpressing IL-8 receptors inhibits neointimal and inflammatory responses to vascular injury in the rat

Interleukin-8 (IL8) is highly expressed by injured arteries in a variety of diseases and is a chemoattractant for neutrophils which express IL8 receptors IL8RA and RB (IL8RA/B) on their membranes. Neutrophils interact with the damaged endothelium and initiate an inflammatory cascade at the site of i...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Giordano, Samantha, Zhao, Xiangmin, Xing, Daisy, Hage, Fadi, Oparil, Suzanne, Cooke, John P., Lee, Jieun, Nakayama, Karina H., Huang, Ngan F., Chen, Yiu-Fai
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865064/
https://ncbi.nlm.nih.gov/pubmed/26801304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00587.2015
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