Targeted Delivery of Pulmonary Arterial Endothelial Cells Overexpressing Interleukin-8 Receptors Attenuates Monocrotaline-Induced Pulmonary Vascular Remodeling

OBJECTIVE: Interleukin-8 (IL8) receptors IL8RA and IL8RB (ILRA/B) on neutrophil membranes bind to IL8 with high affinity and play a critical role in neutrophil recruitment to sites of injury and/or inflammation. This study tested the hypothesis that administration of rat pulmonary arterial endotheli...

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Bibliografische gegevens
Hoofdauteurs: Fu, Jinyan, Chen, Yiu-Fai, Zhao, Xiangmin, Creighton, Judy, Guo, Yuan-Yuan, Hage, Fadi G., Oparil, Suzanne, Xing, Daisy D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180715/
https://ncbi.nlm.nih.gov/pubmed/24790141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.303821
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