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Rederivation of transgenic mice from iPS cells derived from frozen tissue

In mice, induced pluripotent stem (iPS) cells with embryonic stem (ES)-like characteristics have been derived by ectopic expression of four transcription factors in somatic cells: Sox2, Oct3/4, Klf4 and/or c-Myc. To date, iPS cells have only be made from freshly harvested tissues and cells. However,...

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Библиографические подробности
Главные авторы: Lee, Angus Yiu-Fai, Kent Lloyd, K. C.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Netherlands 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018598/
https://ncbi.nlm.nih.gov/pubmed/20397045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-010-9390-9
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