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Sulfation patterns determine cellular internalization of heparin-like polysaccharides

Heparin is a highly sulfated polysaccharide which serves biologically relevant roles as an anticoagulant and anti-cancer agent. While it is well known that modification of heparin’s sulfation pattern can drastically influence its ability to bind growth factors and other extracellular molecules, very...

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Detalhes bibliográficos
Main Authors: Raman, Karthik, Mencio, Caitlin, Desai, Umesh R., Kuberan, Balagurunathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685167/
https://ncbi.nlm.nih.gov/pubmed/23398560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300679a
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