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Heparan sulfate biosynthesis: 6-O-Sulfate groups surprisingly do not affect the action of glucosaminyl N-deacetylase-N-sulfotransferase

Several biologically important growth factor-heparan sulfate (HS) interactions are regulated by HS sulfation patterns. However, the biogenesis of these combinatorial sulfation patterns is largely unknown. N-deacetylase/N-sulfotrasferase (NDST) converts N-acetyl-D-glucosamine residues to N-sulfo-D-gl...

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Udgivet i:FEBS Lett
Main Authors: Raman, Karthik, Nguyen, Thao Kim Nu, Kuberan, Balagurunathan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654310/
https://ncbi.nlm.nih.gov/pubmed/21983289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.09.030
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