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Characterization of uniformly and atom-specifically (13)C-labeled heparin and heparan sulfate polysaccharide precursors using (13)C NMR spectroscopy and ESI mass spectrometry

The biological actions of heparin and heparan sulfate, two structurally related glycosaminoglycans, depend on the organization of the complex heparanome. Due to the structural complexity of the heparanome, the sequence of variably sulfonated uronic acid and glucosamine residues is usually characteri...

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Detalhes bibliográficos
Main Authors: Nguyen, Thao K. N., Tran, Vy M., Victor, Xylophone V., Skalicky, Jack J., Kuberan, Balagurunathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942989/
https://ncbi.nlm.nih.gov/pubmed/20832774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.08.011
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