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Characterization of uniformly and atom-specifically (13)C-labeled heparin and heparan sulfate polysaccharide precursors using (13)C NMR spectroscopy and ESI mass spectrometry

The biological actions of heparin and heparan sulfate, two structurally related glycosaminoglycans, depend on the organization of the complex heparanome. Due to the structural complexity of the heparanome, the sequence of variably sulfonated uronic acid and glucosamine residues is usually characteri...

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Autors principals: Nguyen, Thao K. N., Tran, Vy M., Victor, Xylophone V., Skalicky, Jack J., Kuberan, Balagurunathan
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942989/
https://ncbi.nlm.nih.gov/pubmed/20832774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.08.011
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