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Characterization of uniformly and atom-specifically (13)C-labeled heparin and heparan sulfate polysaccharide precursors using (13)C NMR spectroscopy and ESI mass spectrometry

The biological actions of heparin and heparan sulfate, two structurally related glycosaminoglycans, depend on the organization of the complex heparanome. Due to the structural complexity of the heparanome, the sequence of variably sulfonated uronic acid and glucosamine residues is usually characteri...

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Autori principali: Nguyen, Thao K. N., Tran, Vy M., Victor, Xylophone V., Skalicky, Jack J., Kuberan, Balagurunathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942989/
https://ncbi.nlm.nih.gov/pubmed/20832774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2010.08.011
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