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Sulfation patterns determine cellular internalization of heparin-like polysaccharides
Heparin is a highly sulfated polysaccharide which serves biologically relevant roles as an anticoagulant and anti-cancer agent. While it is well known that modification of heparin’s sulfation pattern can drastically influence its ability to bind growth factors and other extracellular molecules, very...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685167/ https://ncbi.nlm.nih.gov/pubmed/23398560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300679a |
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