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Indole-3-Carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells

We previously established that Indole-3-Carbinol (I3C), a natural hydrolysis product of glucobrassicin in cruciferous vegetables, arrests the proliferation of estrogen-dependent human breast cancer cells and induces protein degradation of estrogen receptor-alpha (ERα). We demonstrate in human MCF-7...

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Detaylı Bibliyografya
Asıl Yazarlar: Marconett, Crystal N., Singhal, Ankur K., Sundar, Shyam N., Firestone, Gary L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684449/
https://ncbi.nlm.nih.gov/pubmed/22835548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.07.008
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