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Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells

MCF7 cells are an estrogen-responsive human breast cancer cell line that expresses both estrogen receptor (ER) α and ERβ. Treatment of MCF7 cells with artemisinin, an antimalarial phytochemical from the sweet wormwood plant, effectively blocked estrogen-stimulated cell cycle progression induced by e...

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Detalhes bibliográficos
Main Authors: Sundar, Shyam N., Marconett, Crystal N., Doan, Victor B., Willoughby, Jamin A., Firestone, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639250/
https://ncbi.nlm.nih.gov/pubmed/18784357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn214
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