1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells

Indole-3-carbinol (I3C), a natural autolysis product of a gluccosinolate present in Brassica vegetables such as broccoli and cabbage, has anti-proliferative and anti-estrogenic activities in human breast cancer cells. A new and significantly more potent I3C analogue, 1-benzyl-I3C was synthesized, an...

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Detalhes bibliográficos
Main Authors: Nguyen, Hanh H., Lavrenov, Sergey N., Sundar, Shyam N., Nguyen, David H.H., Tseng, Min, Marconett, Crystal N., Kung, Jenny, Staub, Richard E., Preobrazhenskaya, Maria N., Bjeldanes, Leonard F., Firestone, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422669/
https://ncbi.nlm.nih.gov/pubmed/20570586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.05.015
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