Two Synthetic Antibodies that Recognize and Neutralize Distinct Proteolytic Forms of the Ebola Virus Envelope Glycoprotein

Ebola Virus (EBOV) is a highly pathogenic member of the family Filoviridae of viruses that causes severe hemorrhagic fever. Infection proceeds through fusion of the host cell and viral membranes, a process that is mediated by the viral envelope glycoprotein (GP). Following endosomal uptake, a key st...

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Autores principales: Koellhoffer, Jayne F., Chen, Gang, Sandesara, Rohini G., Bale, Shridhar, Saphire, Erica Ollmann, Chandran, Kartik, Sidhu, Sachdev S., Lai, Jonathan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684266/
https://ncbi.nlm.nih.gov/pubmed/23111988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201200493
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