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Ebola Virus Glycoprotein: Proteolytic Processing, Acylation, Cell Tropism, and Detection of Neutralizing Antibodies

Using the vesicular stomatitis virus (VSV) pseudotype system, we studied the functional properties of the Ebola virus glycoprotein (GP). Amino acid substitutions at the GP cleavage site, which reduce glycoprotein cleavability and viral infectivity in some viruses, did not appreciably change the infe...

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Detalhes bibliográficos
Main Authors: Ito, Hiroshi, Watanabe, Shinji, Takada, Ayato, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114066/
https://ncbi.nlm.nih.gov/pubmed/11152533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1576-1580.2001
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