Protein Engineering Strategies for the Development of Viral Vaccines and Immunotherapeutics

Autor Koellhoffer, Jayne F., Higgins, Chelsea D., Lai, Jonathan R.
Vydáno 2013

Marburg Virus Glycoprotein GP2: pH-Dependent Stability of the Ectodomain α-Helical Bundle()

Autor Harrison, Joseph S., Koellhoffer, Jayne F., Chandran, Kartik, Lai, Jonathan R.
Vydáno 2012

C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: Effects of conjugation to cholesterol and side chain–side chain crosslinking

Autor Higgins, Chelsea D., Koellhoffer, Jayne F., Chandran, Kartik, Lai, Jonathan R.
Vydáno 2013

Role of Electrostatic Repulsion in Controlling pH-dependent Conformational Changes of Viral Fusion Proteins

Autor Harrison, Joseph S., Higgins, Chelsea D., O'Meara, Matthew J., Koellhoffer, Jayne F., Kuhlman, Brian A., Lai, Jonathan R.
Vydáno 2013

Two Synthetic Antibodies that Recognize and Neutralize Distinct Proteolytic Forms of the Ebola Virus Envelope Glycoprotein

Autor Koellhoffer, Jayne F., Chen, Gang, Sandesara, Rohini G., Bale, Shridhar, Saphire, Erica Ollmann, Chandran, Kartik, Sidhu, Sachdev S., Lai, Jonathan R.
Vydáno 2012

Crystal Structure of the Marburg Virus GP2 Core Domain in its Post-Fusion Conformation

Autor Koellhoffer, Jayne F., Malashkevich, Vladimir N., Harrison, Joseph S., Toro, Rafael, Bhosle, Rahul C., Chandran, Kartik, Almo, Steven C., Lai, Jonathan R.
Vydáno 2012

Conformational Properties of Peptides Corresponding to the Ebolavirus GP2 Membrane-Proximal External Region in the Presence of Micelle-Forming Surfactants and Lipids

Autor Regula, Lauren K., Harris, Richard, Wang, Fang, Higgins, Chelsea D., Koellhoffer, Jayne F., Zhao, Yue, Chandran, Kartik, Gao, Jianmin, Girvin, Mark E., Lai, Jonathan R.
Vydáno 2013

Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species

Autor Koellhoffer, Jayne F., Dai, Zhou, Malashkevich, Vladimir N., Stenglein, Mark D., Liu, Yanyun, Toro, Rafael, S. Harrison, Joseph, Chandran, Kartik, DeRisi, Joseph L., Almo, Steven C., Lai, Jonathan R.
Vydáno 2014

Synthetic Antibodies with a Human Framework That Protect Mice from Lethal Sudan Ebolavirus Challenge

Autor Chen, Gang, Koellhoffer, Jayne F., Zak, Samantha E., Frei, Julia C., Liu, Nina, Long, Hua, Ye, Wei, Nagar, Kaajal, Pan, Guohua, Chandran, Kartik, Dye, John M., Sidhu, Sachdev S., Lai, Jonathan R.
Vydáno 2014