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Role of Electrostatic Repulsion in Controlling pH-dependent Conformational Changes of Viral Fusion Proteins

Viral fusion proteins undergo dramatic conformational transitions during membrane fusion. For viruses that enter through the endosome, these conformational rearrangements are typically pH sensitive. Here we provide a comprehensive review of the molecular interactions that govern pH-dependent rearran...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harrison, Joseph S., Higgins, Chelsea D., O'Meara, Matthew J., Koellhoffer, Jayne F., Kuhlman, Brian A., Lai, Jonathan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701885/
https://ncbi.nlm.nih.gov/pubmed/23823327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.05.009
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