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Role of Electrostatic Repulsion in Controlling pH-dependent Conformational Changes of Viral Fusion Proteins

Viral fusion proteins undergo dramatic conformational transitions during membrane fusion. For viruses that enter through the endosome, these conformational rearrangements are typically pH sensitive. Here we provide a comprehensive review of the molecular interactions that govern pH-dependent rearran...

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Detalhes bibliográficos
Main Authors: Harrison, Joseph S., Higgins, Chelsea D., O'Meara, Matthew J., Koellhoffer, Jayne F., Kuhlman, Brian A., Lai, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701885/
https://ncbi.nlm.nih.gov/pubmed/23823327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.05.009
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