HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

T-cell costimulation and coinhibition generated by engagement of the B7 family and their receptor CD28 family are of central importance in regulating the T-cell response, making these pathways very attractive therapeutic targets. Here we describe HERV–H LTR-associating protein 2 (HHLA2) as a member...

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Ruihua, Chinai, Jordan M., Buhl, Susan, Scandiuzzi, Lisa, Ray, Anjana, Jeon, Hyungjun, Ohaegbulam, Kim C., Ghosh, Kaya, Zhao, Aimin, Scharff, Matthew D., Zang, Xingxing
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683785/
https://ncbi.nlm.nih.gov/pubmed/23716685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303524110
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