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Host B7x promotes pulmonary metastasis of breast cancer

B7x (B7-H4 or B7S1) is an inhibitory member of the B7 family of T cell costimulation. It is expressed in low levels in healthy peripheral tissues such as the lung epithelium, but over-expressed in a variety of human cancers with negative clinical associations including metastasis. However, the funct...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Abadi, Yael M., Jeon, Hyungjun, Ohaegbulam, Kim C., Scandiuzzi, Lisa, Ghosh, Kaya, Hofmeyer, Kimberly A., Lee, Jun Sik, Ray, Anjana, Gravekamp, Claudia, Zang, Xingxing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608819/
https://ncbi.nlm.nih.gov/pubmed/23455497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202439
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