Structure and Cancer Immunotherapy of the B7 Family Member B7x

B7x (B7-H4 or B7S1) is a member of the B7 family that can inhibit T cell function. B7x protein is absent in most normal human tissues and immune cells, but is overexpressed in human cancers and often correlates with negative clinical outcome. The expression pattern and function of B7x suggest that i...

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Publicado no:Cell Rep
Main Authors: Jeon, Hyungjun, Vigdorovich, Vladimir, Garrett-Thomson, Sarah C., Janakiram, Murali, Ramagopal, Udupi A., Abadi, Yael M., Lee, Jun Sik, Scandiuzzi, Lisa, Ohaegbulam, Kim C, Chinai, Jordan M, Zhao, Ruihua, Yao, Yu, Mao, Ying, Sparano, Joseph A., Almo, Steven C., Zang, Xingxing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250833/
https://ncbi.nlm.nih.gov/pubmed/25437562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.053
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