Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

The generation of toxic oligomers during the aggregation of the amyloid-β (Aβ) peptide Aβ42 into amyloid fibrils and plaques has emerged as a central feature of the onset and progression of Alzheimer’s disease, but the molecular pathways that control pathological aggregation have proved challenging...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Cohen, Samuel I. A., Linse, Sara, Luheshi, Leila M., Hellstrand, Erik, White, Duncan A., Rajah, Luke, Otzen, Daniel E., Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683769/
https://ncbi.nlm.nih.gov/pubmed/23703910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218402110
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items