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Letm1, the mitochondrial Ca(2+)/H(+) antiporter, is essential for normal glucose metabolism and alters brain function in Wolf–Hirschhorn syndrome

Mitochondrial metabolism, respiration, and ATP production necessitate ion transport across the inner mitochondrial membrane. Leucine zipper-EF-hand containing transmembrane protein 1 (Letm1), one of the genes deleted in Wolf–Hirschhorn syndrome, encodes a putative mitochondrial Ca(2+)/H(+) antiporte...

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Hlavní autoři: Jiang, Dawei, Zhao, Linlin, Clish, Clary B., Clapham, David E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683736/
https://ncbi.nlm.nih.gov/pubmed/23716663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308558110
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